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This research investigates theta burst stimulation, a neuromodulation technique, as a potential treatment for gambling disorder by measuring changes in craving intensity and relevant biological markers. The study examines whether this brain stimulation approach can reduce gambling cravings and identify associated neurobiological changes in affected patients.
This study examined how personality dimensions and impulsivity traits relate to problematic internet usage among 1,144 online MMORPG and poker players using validated psychological instruments. Neuroticism, negative urgency, positive urgency, and sensation seeking were significantly associated with higher addiction scores, while extraversion showed a protective effect, with similar patterns observed across both gaming groups.
Researchers developed a mannose-modified nanomicelle (Man-LA) designed to deliver hydrogen sulfide directly to the brain via GLUT1 transporters in astrocytes, and demonstrated in rat autism models that it alleviates behavioral symptoms while promoting aerobic glycolysis and protecting hippocampal neurons. The study identifies dysregulation of astrocytic aerobic glycolysis and H₂S signaling as potentially important in autism pathophysiology, though these findings remain preclinical and require human validation.
Researchers developed a method to identify which genetic networks discovered in model organisms (yeast, neurons, mice) are most relevant to human Parkinson's disease. This translational genetics approach bridges the gap between basic research findings and actual human disease mechanisms.
This narrative review examines how mild traumatic brain injury (mTBI) affects the hypothalamic-pituitary-ovarian axis, particularly in females who experience disproportionately worse outcomes and higher rates of menstrual dysfunction post-injury. The authors synthesize evidence on sex differences, pituitary hormone regulation, and downstream reproductive health consequences to identify research gaps and clinical recommendations for female mTBI patients.
