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AVC și AIT

Accident vascular cerebral și recuperare, la orice vârstă.

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StudiuAVC și AITÎncredere bună19.06.2026

Multidimensional Study of Antiplatelet Therapy and CYP2C19 Genetic Testing in Ischemic Stroke and TIA Patients

This study evaluates current practices and guideline adherence for antiplatelet therapy and CYP2C19 genetic testing in stroke and TIA patients, combining systematic guideline review with retrospective analysis of 147 patients and physician interviews. Results show most patients received guideline-concordant empirical dual antiplatelet therapy, though genetic testing uptake was low, with recommendations for precision pharmaceutical care implementation.

StudiuAVC și AITÎncredere înaltă19.06.2026

Adherence Trajectories to Statins and Antithrombotic Therapy After Ischemic Stroke and Cardiovascular Outcomes

This longitudinal study of over 13,000 stroke survivors identified four distinct patterns of adherence to secondary prevention medications, ranging from sustained high adherence to early or gradual discontinuation. Patients maintaining dual high adherence to both statins and antithrombotic agents achieved the best lipid control and lowest mortality, while those with early discontinuation faced significantly elevated risks of recurrent stroke and other cardiovascular events.

StudiuAVC și AITÎncredere înaltă19.06.2026

Management of Large Artery Atherosclerosis

Large artery atherosclerosis is a major cause of ischemic stroke and transient ischemic attack with high recurrence risk. Current best practices emphasize aggressive management of modifiable risk factors (hypertension, hyperlipidemia), appropriate antithrombotic therapy for secondary prevention, and careful patient selection for revascularization procedures.

StudiuAVC și AITÎncredere înaltă19.06.2026

Stroke risk factors and outcomes in Trinidad and Tobago: the START study

A cross-sectional study of 546 patients admitted with acute neurologic deficits identified 410 stroke cases (80% ischemic, 19% hemorrhagic) with 16% inpatient and 26% three-month mortality rates. Key findings included chronic kidney disease as a significant risk factor for hemorrhagic stroke and diabetes mellitus as a risk factor for both ischemic and hemorrhagic stroke types.

StudiuAVC și AITÎncredere bună19.06.2026

Stroke in Autoimmune Rheumatic Diseases

This article examines the relationship between autoimmune rheumatic diseases and increased stroke risk in affected patients. The content appears to address pathophysiological mechanisms and clinical implications of stroke complications in this patient population.

StudiuAVC și AITÎncredere bună19.06.2026

Lipoprotein(a) Levels and Association with Ischemic Stroke Severity and Disability

This study of 300 ischemic stroke patients found that elevated lipoprotein(a) (≥75 nmol/l) was associated with greater acute neurological deficits, longer hospital stays, and worse functional outcomes at discharge and 90 days. The findings suggest lipoprotein(a) may be relevant to stroke severity and recovery, though causality was not established.

StudiuAVC și AITÎncredere înaltă19.06.2026

Intracranial atherosclerotic stenosis associated with 1-year cognitive impairment after acute ischemic stroke or TIA

A prospective cohort study of 1,261 stroke/TIA patients found that intracranial atherosclerotic stenosis (≥50% arterial narrowing) independently predicted cognitive impairment at 12 months, even after adjusting for other vascular risk factors and brain imaging markers. The association remained significant with cognitive impairment defined as Montreal Cognitive Assessment score <23.

StudiuAVC și AITÎncredere înaltă19.06.2026

Home-Based RESIST: A Multicenter RCT of Structured Physical Exercise for Symptomatic Intracranial Artery Stenosis

This multicenter randomized controlled trial investigates whether home-based structured physical exercise combined with usual care reduces recurrent stroke risk in patients with symptomatic intracranial artery stenosis compared to usual care alone. The study enrolls 1,300 patients in China with primary outcomes measured at 1 year including recurrent ischemic stroke and secondary outcomes including transient ischemic attack and hemorrhagic stroke.