Îngrijorare excesivă, tensiune, atacuri de panică.
73 de articoleThis systematic review examines cognitive deficits in GAD patients, including attention, executive function, and working memory impairments, alongside neural correlates such as amygdala and insula hyperactivity. The paper synthesizes findings on evidence-based treatments including CBT and mindfulness while identifying gaps requiring further investigation into GAD's underlying mechanisms.
This cross-sectional study examined self-compassion levels in adolescents with and without anxiety disorders, finding that clinical groups showed significantly lower overall self-compassion and higher uncompassionate self-responding. Results suggest that reducing self-directed criticism may help buffer against anxiety symptoms, though the specific protective mechanisms of compassionate versus uncompassionate self-responding warrant further investigation.
This is a study protocol for a rigorous randomized controlled trial examining whether lavender aromatherapy can reduce benzodiazepine use in patients with generalized anxiety disorder and panic disorder. The trial measures primary outcomes as the frequency of anxiolytic medication use over 28 days, with proper blinding and placebo controls.
This systematic review synthesizes evidence-based pharmacotherapy for pediatric GAD, finding that combination psychotherapy and pharmacotherapy yields better outcomes than monotherapy. SSRIs are recommended as first-line treatment with faster symptom reduction, while SNRIs serve as a second-line option, both showing moderate effect sizes in clinical trials.
This epidemiological study analyzed data from India's National Mental Health Survey covering 34,802 adults and found a 0.47% prevalence of social anxiety disorder, with male gender, unemployment, and urban residence as risk factors. Individuals with SAD experienced significant functional impairment across work and social domains, with 82% not receiving treatment despite high rates of comorbid psychiatric conditions.
This study examined the association between cannabis use and social anxiety disorder (SAD) in 5,194 emerging adults (ages 18-25) from a nationally representative sample, finding 1.10% prevalence of co-occurring use and SAD. White race, part-time or non-student status, and comorbid mood/anxiety disorders were significantly associated with co-occurring cannabis use and SAD.
This research examines the cognitive and behavioral mechanisms underlying social anxiety disorder in adolescents. The study investigates evidence-based psychological processes relevant to understanding and treating social anxiety in this age group.
Generalized Anxiety Disorder (GAD) is characterized by excessive, uncontrollable worry lasting at least six months that significantly impairs functioning, with genetic factors contributing to susceptibility. The condition involves alterations in amygdala function and GABA neurotransmitter dysregulation, presenting with symptoms including restlessness, sleep difficulties, irritability, and physical manifestations like trembling and sweating.
This study examined cognitive distortions across three anxiety disorders in 150 clinical patients and 91 controls using validated assessment scales. Cognitive distortions were significantly higher in panic disorder, GAD, and social anxiety disorder, with disorder-specific patterns identified (e.g., personalization more severe in SAD; mental filtering in GAD).
This systematic review evaluated the feasibility of using digital phenotyping—extracting mental health markers from smartphone and device interactions—to predict symptom relapse or exacerbation in mental health patients. Analysis of 29 peer-reviewed studies found digital phenotyping applied primarily to schizophrenia, mood disorders, and anxiety disorders, offering potential for remote mental health monitoring.
This retrospective cohort study examined antidepressant prescribing patterns in 131 transgender and nonbinary adults diagnosed with gender dysphoria and concurrent mood or anxiety disorders between 2005-2021. Key findings include no significant difference in overall antidepressant prescriptions across gender identities at diagnosis, higher bupropion use in transgender females, and that 38% of patients lacked active antidepressants despite mood/anxiety diagnoses.
This study evaluated the reliability and validity of the GAD-7 anxiety screening tool in 278 postpartum Polish mothers, finding excellent internal consistency (Cronbach's Alpha = 0.90) and strong correlations with depression and stress measures. Confirmatory factor analysis confirmed the questionnaire's structural validity and suitability for assessing postpartum anxiety in this population.
This study compared emotional experiences of 88 participants (44 with social anxiety disorder, 44 without) over 21 days using daily experience sampling. Individuals with SAD reported higher anger levels, particularly during interactions with distant others, and showed a unique pattern where daily anger predicted increased anxiety the following day, suggesting anger may maintain anxiety symptoms in SAD.
This open-label pilot study examined the feasibility of intensive 4-day cognitive behavior therapy for social anxiety disorder in 30 patients, using validated outcome measures including the Liebowitz Social Anxiety Scale, GAD-7, and PHQ-9. Results showed large effect sizes for social anxiety symptoms and secondary improvements in generalized anxiety and depression, with 55% remission and 90% treatment response rates at 3-month follow-up.
This systematic review synthesizes evidence for treating social anxiety disorder, recommending SSRIs as first-line pharmacotherapy and cognitive behavioral therapy as the primary psychological intervention. Additional effective options include monoamine oxidase inhibitors, benzodiazepines, pregabalin, and psychodynamic approaches, with psychological interventions showing better long-term tolerability.
This retrospective cohort study analyzed electronic health records from 2011-2020 to compare the risk of new-onset anxiety disorders in patients with hidradenitis suppurativa (a chronic skin condition) versus controls. Patients with HS had significantly higher incidence rates of anxiety disorders (5.74 vs 3.86 per 100 person-years), with adjusted analysis showing elevated risk even after controlling for demographic and clinical confounders.
A longitudinal study of 309 adolescents found that elevated startle reflex responses to unpredictable (but not predictable) threat at age 15 predicted the onset of generalized anxiety disorder by age 18, independent of prior anxiety history. Startle responses did not predict social anxiety disorder or depression, suggesting this biomarker is specific to GAD development risk.
This neuroimaging study compared brain cortical folding patterns in 90 panic disorder patients (30 with comorbid GAD, 60 without) and 65 healthy controls using MRI analysis. Results showed increased cortical gyrification in fear-network regions in panic disorder, with additional hypergyrification in worry-related brain areas specifically in the comorbid group, and correlations between cortical measures and suicidality/avoidance behaviors.