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ADHD

Atenție, impulsivitate și hiperactivitate.

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StudiuAutism + ADHDÎncredere înaltă21.06.2026

Epidemiological Study of Traumatic Brain and Spinal Injuries in Pediatric Patients: One-Year Analysis of Prevalence, Causes and Trends in Bulgaria

This retrospective study analyzed medical records of pediatric patients (under 18 years) admitted to a Bulgarian hospital emergency department over one year to determine prevalence, causes, and trends of traumatic brain and spinal cord injuries. Among 38,504 emergency department visits, 32% were children, with 0.3% hospitalized for neurosurgical conditions including TBI and SCI.

StudiuAutism + ADHDÎncredere bună21.06.2026

Relationship between depression and sex steroid hormones in women with epilepsy

This study investigated associations between sex steroid hormones, antiseizure medications, and depression in 112 women with epilepsy compared to 50 healthy controls, finding a 18.8% depression prevalence and significant hormonal differences including elevated testosterone and altered FSH, estradiol, progesterone, and prolactin levels. Sex steroid hormones emerge as potential biomarkers for depression risk in women with epilepsy, with implications for treatment and prognosis.

StudiuAutism + ADHDÎncredere bună21.06.2026

Neuropsychiatric Disorders and Burn Trauma: Clinical Epidemiology from a Tertiary Hospital

A prospective observational study over 24 months analyzed burn injury characteristics in patients with underlying neuropsychiatric conditions, finding epilepsy as the most common disorder (66.52%) followed by intellectual disability and dementia. Female patients experienced higher rates of severe burns and scalding injuries with more frequent third-degree burns and head/neck involvement compared to males.

StudiuAutism + ADHDÎncredere bună21.06.2026

Psychiatric Comorbidities in Functional Neurological Disorders and Psychogenic Non-Epileptic Seizures: Systematic Review and Policy Recommendations

This systematic review examines psychiatric comorbidities associated with Functional Neurological Disorders (FND) and Psychogenic Non-Epileptic Seizures (PNES), finding these are not autonomous conditions but develop alongside autism, borderline personality disorder, PTSD, and alexithymia. The authors propose a biopsychosocial model where early trauma, abuse, and neglect contribute to progressive neurological sensitivity, particularly in young female patients, and recommend improved assessment and integrated treatment policies.

StudiuAutism + ADHDÎncredere bună21.06.2026

Anxiety and Depression after Spinal Cord Injury: A Cross-Sectional Study

This study examined the prevalence of depression and anxiety in individuals with subacute and chronic spinal cord injury using validated psychological assessment tools (BDI and STAI scales). Results showed significant alterations in both depression and anxiety levels, with differences noted between subacute and chronic phases; early psychological assessment and intervention are recommended to prevent cognitive and mental health complications.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Epileptic variant in the spectrum of Alzheimer's disease - practical implications

Alzheimer's disease carries increased epilepsy risk not only in advanced stages but also during mild cognitive impairment and preclinical stages, with seizures sometimes being the earliest clinical manifestation (epileptic variant of AD). This presentation offers a therapeutic window where antiseizure medications may help prevent cognitive decline by addressing AD-related brain hyperexcitability, but requires biomarker assessment (amyloid and tau) for accurate diagnosis.

StudiuAutism + ADHDÎncredere bună21.06.2026

Depression and ADHD as predictors of exercise addiction: A cross-sectional study in frequent exercisers

This cross-sectional study of 173 frequent exercisers (>10 hours/week) examined relationships between depression, ADHD symptoms, and exercise addiction using standardized scales and regression analyses. Depressive and ADHD symptoms were significantly positively correlated with exercise addiction symptoms, with depression emerging as the stronger predictor after controlling for age and gender.

StudiuAutism + ADHDÎncredere bună21.06.2026

Combat readiness, alcohol abuse, and posttraumatic stress disorder among Uganda People's Defence Forces soldiers

A cross-sectional study of 150 UPDF soldiers returning from deployment found 16% screened positive for PTSD and 21% for moderate substance use disorder. Combat readiness training was associated with reduced risk of both PTSD and alcohol abuse, with alcohol use mediating the relationship between combat readiness and PTSD symptoms.

StudiuAutism + ADHDÎncredere bună21.06.2026

Psychedelic Research for Alcohol Use Disorder with Comorbid Major Depressive Disorder: An Unmet Need

This narrative review examines evidence for psilocybin- and LSD-assisted treatment in patients with both alcohol use disorder and major depressive disorder, noting promising sustained effects on drinking frequency and symptom reduction. The authors argue for integrated therapeutic approaches using psychedelics to simultaneously address the high-prevalence comorbidity, while discussing methodological considerations for future clinical trials.

StudiuAutism + ADHDÎncredere bună21.06.2026

Long-term changes in behavioral addiction symptoms among adults with ADHD treated with methylphenidate

A one-year prospective study of 37 adults with ADHD found that methylphenidate treatment significantly reduced symptoms of internet, shopping, food, and sex addictions, with the proportion of patients having at least one behavioral addiction diagnosis decreasing from 51.4% to 35.1%. Changes in cognitive impulsivity, sluggish cognitive tempo, and mood/anxiety symptoms correlated moderately with improvements in internet addiction scores.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Infantile Spasms in Pediatric Down Syndrome: Neurobiological Mechanisms and Therapeutic Approaches

This review examines why infantile spasms commonly occur in Down syndrome by analyzing animal models (Ts65Dn and TcMAC21 mice) to identify abnormalities in brain excitation and inhibition, particularly involving GABA receptor dysfunction. The research provides insights into potential therapeutic targets by clarifying the neurobiological mechanisms underlying seizure predisposition in Down syndrome.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Effect of Educational Interventions on Psychiatrists' Adherence to Treatment Guidelines for Schizophrenia and Depression: A Multicenter Implementation Study

The EGUIDE project evaluated how educational lectures on clinical practice guidelines influenced 782 psychiatrists' treatment practices across 176 Japanese hospitals, comparing guideline adherence in over 11,000 patients with schizophrenia or major depressive disorder. Psychiatrists who participated in guideline education showed higher rates of guideline-recommended treatments including appropriate antipsychotic monotherapy and reduced unnecessary psychotropic co-prescriptions.

StudiuAutism + ADHDÎncredere bună20.06.2026

Validation of the 10-Item Depression, Anxiety and Stress Scale in Mild Traumatic Brain Injury Patients

This study evaluated the psychometric properties of the DASS-10 in 354 treatment-seeking adults with mild TBI, finding good fit to the Rasch model with high internal consistency and acceptable unidimensionality. Results support the DASS-10 as a reliable, brief screening tool for psychological distress in post-mild TBI outpatient populations.

StudiuAutism + ADHDÎncredere bună20.06.2026

Pathogenesis of Comorbid Epilepsy in Alzheimer's Disease and the Role of Perampanel as an AMPA Receptor Inhibitor

Alzheimer's disease and epilepsy frequently co-occur and share common pathogenic mechanisms involving AMPA-type glutamate receptors. Perampanel, an FDA-approved AMPAR antagonist for seizure management, may offer therapeutic benefits in patients with comorbid AD-epilepsy, particularly those with myoclonus or sleep disturbances, though clinical evidence remains limited.

StudiuAutism + ADHDÎncredere bună20.06.2026

Persistent psychiatric symptoms in apparently well-controlled epilepsy: case report

A case of a middle-aged woman with well-controlled epilepsy who presented with persistent anxiety, depression, and irritability despite adequate psychiatric medication (escitalopram, olanzapine). Investigation revealed temporal lobe epilepsy auras as the underlying cause, and adjustment of anti-seizure therapy with lacosamide resulted in complete symptom resolution and significant functional improvement.

StudiuAutism + ADHDÎncredere înaltă20.06.2026

Mental Health Problems in Traumatic Spinal Cord Injury Patients: An Umbrella Systematic Review

This umbrella systematic review synthesized 20 systematic reviews to assess the prevalence and correlates of mental illness in traumatic spinal cord injury patients, finding depression (up to 43%), PTSD (up to 62%), anxiety (27%), and hazardous alcohol use (≥50%) as major concerns. Common risk factors included pain, injury severity, low social support, and maladaptive coping, though evidence for effective interventions was limited.