Cotard's Delusion in Major Depressive Disorder With Psychotic Features: A Case Report

This case report describes a 44-year-old man with major depressive disorder and psychotic features who experienced Cotard's delusion (false belief that parts of his body were decaying or that he was dead). The patient showed limited response to various antidepressant-antipsychotic combinations but achieved substantial improvement with venlafaxine monotherapy, highlighting the need for further research into optimal pharmacological treatments for this rare condition.