Transdiagnostic conceptualization of schizophrenia and autism spectrum disorder: An integrative framework of minimal self disturbance

This literature review proposes that autism spectrum disorder and schizophrenia share overlapping phenomenological and neural mechanisms centered on anomalous minimal self-experience, including altered body ownership and sense of agency. The framework integrates findings from phenomenology, neurocognition, and neural imaging, showing that while both conditions feature self-disturbances, they manifest differently—with schizophrenia patients showing heightened body ownership alterations and autistic individuals showing decreased susceptibility.