Unraveling the Role of Wnt Signaling Pathway in the Pathogenesis of Autism Spectrum Disorder: A Systematic Review

This systematic review examines evidence from animal models linking dysregulation of the Wnt signaling pathway to autism pathogenesis across molecular, cellular, and physiological levels. The authors identify this pathway as a potential future therapeutic target, noting that drugs affecting Wnt signaling can reduce autistic-like behaviors in animal models.