Case Report: Generalized Anxiety Disorder and Hypertension—Bidirectional Relationship Addressed Through Integrated Management

A 61-year-old patient with treatment-resistant hypertension and anxiety following thyroidectomy was treated with a multimodal approach combining antidepressants, transcranial magnetic stimulation, biofeedback, and psychotherapy, achieving significant reductions in blood pressure (176/105 to 125/72 mmHg) and anxiety severity. The case illustrates the bidirectional neuroendocrine relationship between anxiety and hypertension, with improvements sustained at 6-month follow-up and reduced antihypertensive medication requirements.