Asociația dintre nivelurile serice de TNF-α și deficiența memoriei imediate în tulburarea depresivă majoră: un studiu pilot

This pilot study examined whether elevated tumor necrosis factor-alpha (TNF-α), a pro-inflammatory cytokine, correlates with cognitive deficits in major depressive disorder. In 60 MDD patients versus 60 controls, higher TNF-α levels were significantly associated with lower immediate memory scores, suggesting neuro-inflammatory mechanisms may contribute to cognitive impairment in depression.