Comprehensive multi-omics mapping of immune perturbations in autism spectrum disorder

This study used advanced profiling techniques including flow cytometry, single-cell RNA sequencing, and plasma biomarker analysis to characterize immune dysregulation in autism spectrum disorder. The research identified significant alterations in T cells, natural killer cells, and inflammatory markers that correlated with clinical severity, implicating interferon-driven and antiviral signaling pathways in ASD immune pathology.