Psychiatric Comorbidities Associated with Hormonal Contraceptive Use: A Scoping Review and Meta-Analysis (2014–2024)

This systematic scoping review synthesized evidence from 46 studies (2014–2024) on associations between hormonal contraceptive use and psychiatric outcomes. Meta-analysis found small but statistically significant increases in depressive symptoms with progestin-only methods (RR=1.24) and inconsistent evidence for anxiety and suicidality, with high heterogeneity across studies highlighting the need for individual risk assessment.