Clinical Characteristics and Disease Course of Pediatric-Onset Multiple Sclerosis in Kuwait

This retrospective study examined 249 pediatric MS patients in Kuwait, finding a predominantly female cohort (70.3%) with mean onset age 15 years, most presenting with brainstem/cerebellar symptoms. Most patients remained in relapsing-remitting phenotype during follow-up, though disease breakthrough occurred in 36.1% of cases, prompting escalation or switching of disease-modifying therapies.