Dyslipidemia phenotypes and lipoprotein particle distributions in multiple sclerosis

This cross-sectional study examined lipid profiles and lipoprotein particle characteristics in 203 healthy controls, 221 patients with relapsing-remitting MS, and 126 with progressive MS, using advanced NMR profiling and immunoassay methods. Results showed similar dyslipidemia frequency across groups but progressive MS exhibited altered triglyceride-rich and LDL particle concentrations, with lower disability scores associated with higher HDL particle levels.