Multicenter Open-Label Trial of Ginkgo Biloba Extract EGb 761® for Cognitive Decline in Major Neurocognitive Disorder

A prospective study of 150 patients aged 50+ with Alzheimer's disease or vascular dementia receiving 120 mg of Ginkgo biloba extract twice daily for 18 weeks demonstrated significant improvements in constructional praxis, memory, executive function, and behavioral symptoms using validated cognitive measures. Adverse events were reported in 22% of patients, with no serious safety concerns identified.