Wnt Pathway, APP Processing, and Telomere Shortening in Down Syndrome Adults

This research examines molecular mechanisms in Down syndrome adults, focusing on how Wnt signaling pathway dysfunction, amyloid precursor protein (APP) processing abnormalities, and accelerated telomere shortening may contribute to cellular aging and neurological complications. The study investigates potential biomarkers and mechanistic links between chromosomal imbalance and age-related cellular processes in this population.