Autologous Stem Cell Transplantation for Multiple Sclerosis: Current Evidence and Clinical Applications

This review examines autologous hematopoietic stem cell transplantation (AHSCT) as an emerging therapeutic option for patients with relapsing-remitting MS who are resistant to disease-modifying therapies, demonstrating sustained remission and lower relapse rates compared to conventional treatments. While AHSCT shows promise in preventing progression and improving neurological outcomes, results are mixed in progressive MS cases, and further research is needed to identify optimal patient selection and transplant protocols.