Early neurorehabilitation after traumatic brain injury reduces Parkinson's disease risk: A retrospective cohort study

This retrospective cohort study examined 3,500+ patients with moderate to severe TBI and found that immediate neurorehabilitation (within 1 week) reduced the risk of developing Parkinson's disease at 3 and 5 years compared to delayed rehabilitation (8 days to 6 months). The protective effect was demonstrated through both PD incidence and medication prescription outcomes using propensity score-matched analysis.