Endoscopic and surgical evaluation of epiphora in children with Down syndrome

This retrospective study examined 63 children with Down syndrome presenting with primary epiphora (excessive tearing), finding that 67% had symptoms from birth. Surgical interventions including office-based probing and endoluminal lacrimal duct recanalization achieved complete or partial symptom resolution in 94% of 18 treated patients, with dacryoendoscopy revealing both developmental anomalies and chronic inflammatory changes in the lacrimal drainage system.