Pupillary Dilation in Adolescent with Psychogenic Non-epileptic Seizures: Clinical Case Report

A 16-year-old female with trauma history and mood disorder presented with recurrent psychogenic non-epileptic seizures (PNES) during hospitalization, characterized by unresponsiveness, irregular movements, and sympathetic activation including pupillary dilation. Video-EEG monitoring ruled out epileptic activity, confirming PNES diagnosis; treatment with sertraline and behavioral strategies including mindfulness resulted in symptom reduction and improved psychiatric outcomes by discharge.