Morbidity and mortality in alcohol use disorder: genetic and demographic risk factors in an 18-year follow-up study

This 18-year longitudinal study of 360 Swedish patients treated for severe alcohol withdrawal examined whether comorbid substance use, demographics, and the ANKK1 A1 allele predicted mortality outcomes. Male sex and age were the strongest predictors of early death in AUD patients, while poly-substance users showed higher psychiatric comorbidity and traumatic causes of death.