Arhitectură cu dublă engrame într-un tip celular striatal care controlează distinct recăderea în alcool și extincția

This neuroscience study demonstrates that two functionally distinct groups of neurons (dMSNs) in the striatum encode opposing memories: one promotes relapse to alcohol use while the other supports extinction learning. The findings suggest that relapse is driven by persistent synaptic strengthening in alcohol-associated neural circuits, providing potential targets for therapeutic intervention in addiction treatment.