Shared Genetic Architecture Between Testosterone Traits and ADHD: A Genomic Analysis

StudiuADHDÎncredere înaltă

This genomic study identifies genetic correlations and overlapping loci between ADHD and testosterone traits (total testosterone, bioavailable testosterone, and SHBG) using GWAS data and causal mixture modeling. Results show 22-51 shared genomic loci involved in signal transduction and neural development pathways, suggesting a biological basis for sex differences in ADHD susceptibility.

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