Sensory Processing Risk Markers for Schizophrenia in Autism Spectrum Disorder: Systematic Review and Meta-Analysis

This systematic review and meta-analysis examined whether basic sensory neurophysiological impairments characteristic of schizophrenia are similarly present in autism spectrum disorder across 44 studies measuring prepulse inhibition, P50 suppression, and mismatch negativity. Findings revealed some shared markers but also key differences—particularly increased N100 amplitudes in autism opposite to the schizophrenia pattern—suggesting distinct sensory profiles between the conditions.